CARTIGEN FORTE

Cartigen Forte is a comprehensive formula containing natural ingredients: Glucosamine, Chondroitin and Methyl Sulfonyl Methane (MSM) along with essential vitamins and minerals used to support joint health. Glucosamine available in Cartigen forte is in the preferred crystalline form, which offers good absorbability and also longer duration of action.

BENEFITS

• • Helps reduce pain, disease progression and improve joint mobility in osteoarthritis
  • Helps stimulate cartilage synthesis & delay cartilage degeneration
  • Helps stimulate cartilage repair & prevent cartilage breakdown
  • Helps to reduce inflammation and swelling

Dedicated name of the product

Bio Basic Men

The general name of the product

Glucosamine, Chondroitin, MSM, Vitamins, Minerals & antioxidants

Indication & usage

Treatment of osteoarthritis, rheumatoid arthritis, joint pain and tenderness, back pain, stiffness and swelling, movement restrictions associated with osteoarthritis

Composition

Each film coated tablet contains: Glucosamine Sulphate Potassium Chloride 750 mg equivalent to Glucosamine sulphate 563 mg, Chondroitin Sulfate Sodium 100 mg, Methyl Sulfonyl Methane 250 mg, Vitamin D3 200 IU, Vitamin E 12.5 mg, Vitamin C 30 mg, Sodium Selenite equivalent to Selenium 70 mcg, Zinc Sulphate Monohydrate equivalent to elemental Zinc 4mg, Manganese Sulphate equivalent to elemental Manganese 3 mg, Chromium Picolinate equivalent to elemental Chromium 50 mcg, Copper Sulphate Pentahydrate equivalent to elemental Copper 0.5 mg, Sodium Borate equivalent to elemental Boron 0.5 mg.

Pharmacology and pharmacokinetics functions of the product

Cartigen Forte is combination of high-strength pharmaceutical grade glucosamine, chondroitin sulphate, methyl sulfonyl methane, vitamins, minerals and antioxidants.

Glucosamine acts as a fundamental building block for the biosynthesis of glycosaminoglycans, hyaluronate, and proteoglycans, which are important for collagen synthesis, degradation of which lead to the disease termed as osteoarthritis (OA). Moreover, glucosamine sulfate exhibits anti-inflammatory and chondroprotective actions and thus has been shown to alleviate pain and even restore or stimulate articular cartilage formation in patients with damaged cartilages in affected joints with osteoarthritis.

Chondroitin sulphate is natural glycosaminoglycan, present in the extracellular matrix of the resilient cartilage tissues. Apart from that it reduces the formation of pro-inflammatory cytokines and pro-inflammatory enzymes, such as phospholipase A2, cyclooxygenase 2 (COX – 2) and nitric oxide synthase. It also exhibits chondroprotective properties. Studies have shown that combined action of glucosamine sulphate and chondroitin sulphate has been shown to delay radiological progression of osteoarthritis.

Methyl sulfonyl methane (MSM) is a naturally occurring Sulphur compound found in minimal quantities in food and human blood, Methyl sulfonyl methane improves lubrication, cartilage synthesis, and reduces inflammation. It provides essential Sulphur, which is used by the chondrocytes for the formation of proteins and collagen (connective tissue). It has powerful antioxidant action and has been shown to exert analgesic and anti-inflammatory actions as well.

Minerals and vitamins provide antioxidant action to reduce inflammation to the joint and supply necessary vitamins, which are the key components of cartilage tissues.

Dosage and administration

One tablet twice a day or as directed by the physician. Swallow with a glass of water, not to be chewed. Do not exceed the recommended intake.

Contraindications

Patients, who are allergic to shellfish, should consult physician before using glucosamine products.

Side effects

Gastrointestinal disturbances, drowsiness, headache, insomnia and mild temporary digestive complaints such as abdominal pain, poor appetite, nausea, heartburn, constipation, diarrhea and vomiting may be seen at higher doses. In rare cases the combination of glucosamine and chondroitin leads to a temporary elevated blood pressure, heart rate and palpitations.

Warning & Precautions

Cartigen forte should be taken only under the supervision of a health care provider because of its potential side effects and interactions with medications. The patients with diabetes mellitus should monitor the blood glucose levels during and the initiation of the treatment.

Interactions

Glucosamine and chondroitin sulfate may interact with anticoagulants such as acenocoumarol, anisidine, dicoumarol, aspirin, warfarin and warfarin potassium. Precaution, when using concomitant medication is recommended as the possibility of interactions cannot be excluded.

Usage in pregnancy & lactation

No controlled studies are available for use in pregnancy & lactation, should be given only if the potential benefit justifies the potential risk to the fetus. Consult your health care provider before use.

Packaging information

Pack of 2×15’s Tablets

Condition for preservation and storage

Store below 30⁰ C, Protect from light & moisture. Keep out of reach of children.

Producing country name

Iran

Manufacturing company name

Manufactured By: KMP
Trademark & IRC Holder : Abba Darou Teb